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A number of autoimmune disease models have been used to examine the antiinflammatory and immunosuppressive effects of tolerogenic dendritic cells (tDCs) The Rosiglitazonemediated dendritic cells ameliorate collageninduced arthritis in mice Biochem Pharmacol 2016 Sep 11158593 doi 101016/jbcp201605009 Epub 2016 May 18 Authors SeiHee Byun 1 Jun.

PD1 blockade induces responses by inhibiting adaptive

Therapies that target the programmed death1 (PD1) receptor have shown unprecedented rates of durable clinical responses in patients with various cancer types One mechanism by which cancer tissues limit the host immune response is via upregulation of PD1 ligand (PDL1) and its ligation to PD1 on.

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